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The Justice Coalition represents victims across the nation who have suffered from bone loss or kidney problems after taking Truvada. If you or a loved one has experienced these side effects, you may be entitled to compensation from Truvada’s manufacturer, Gilead Sciences.
Truvada is one of the most frequently prescribed drugs for the treatment of symptoms related to HIV (Human Immunodeficiency Virus) and AIDS (Acquired Immune Deficiency Syndrome). Truvada is manufactured and market by Gilead Sciences which was granted approval for its first Tenofovir Disoproxil Fumarate (TDF) medication in 2001.
Lawsuits filed by patients with HIV allege that Gilead suppressed a safer version of the drug with far less toxicity in order to maximize profits by extending the sales of the initial TDF drug. In the late 1990s when Gilead was developing treatments for HIV, their own lab testing proved TAF (Tenofovir Alafenamide) was an effective and safer alternative because it released fewer toxins into the body and therefore placed less strain on the kidneys to filter out the waste. The strain of expelling the drug’s high level of toxins can lead to kidney damage and kidney failure. Rather than seeking FDA approval for the safer TAF option, Gilead sought and was granted approval in 2001 for the TDF based medication Viread, a precursor to Truvada.
Despite the knowledge of a safer alternative drug, Gilead did not release TAF based medications until just a few years ago. Their decision put many patients who were already suffering with HIV at a greater risk of developing kidney problems and bone density issues. The decision also rewarded drug manufacturer Gilead Sciences with millions of dollars in additional revenue as the out-of-pocket cost for Truvada reached an astronomical $2,000 per month for many HIV and AIDS patients.
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Tenofovir Disoproxil Fumarate (TDF) is the active ingredient for a class of antiretroviral drugs known as Nucleoside Reverse Transcriptase Inhibitors (NRTIs) commonly used to treat HIV. The drugs stop HIV from multiplying by blocking an enzyme in the body called Reverse Transcriptase. TDF drugs are prescribed in combination with other medications to help improve the quality of life for those living with HIV. All five of the TDF drugs on the market today are produced by Gilead Sciences. In 2017 alone, these drugs generated a combined $11 billion in revenue for Gilead.
Chronic kidney disease or chronic kidney failure is the gradual loss of the kidney’s ability to filter waste and excess fluids out of the blood. Once chronic kidney disease has reached an advanced stage, dangerous levels of electrolytes and waste can build up in the blood. However, in the early stages, you may have very few signs or symptoms that you are suffering from kidney disease. Often the disease does not become apparent until kidney function is significantly impaired. According to the Mayo Clinic, common symptoms of chronic kidney disease include:
